Congratulations Dr Oi Wei Mak and Nabangshu Sharma for our new paper in Bioorganic & Medicinal Chemistry Letters! In this work, Oi Wei applied virtual screening to identify novel inhibitors that disrupt the binding interactions between Hsp90 C-terminal domain and its co-chaperones. This was confirmed experimentally by Oi Wei and Nabangshu. Thanks also to our collaborator Dr Jóhannes Reynisson of Keele University (and formerly University of Auckland) for your help.
You can read our paper here: https://doi.org/10.1016/j.bmcl.2021.127857