Eva’s PhD Thesis Submission

Congratulations Eva for submitting her PhD thesis for examination today. Eva joined us in November 2017. Her PhD focused on the application of biophysical and biochemical techniques to study protein-ligand interactions and enzyme inhibition. Eva worked on a diverse range of projects during her PhD. Of particular highlights are (1) experimentally validating the use of … Read more

Virtual Seminar at North Carolina State University

Ivan gave a virtual seminar at the Department of Molecular and Structural Biochemistry of North Carolina State University this morning. Ivan covered several topics in the seminar, including our work on bacterial enzymes that are involved in infectious disease, the use of chemical biology tools to identify and validate enzyme targets in glioma cells, and … Read more

New Paper in Frontiers of Chemistry

Congratulations Dr Nabangshu Sharma for his new paper in Frontiers of Chemistry (Impact factor: 5.221). This is Nabangshu’s second “first author” paper in as many months. The paper describes Nabangshu’s studies of a novel thermophilic laccase from Geobacillus yumthangensis, and its potential as a biocatalyst to degrade organic pollutants. This is an invited paper and … Read more

MSc Progress Review by Junlang and Vito

Vito and Junlang gave their MSc progress review today. Junlang gave an excellent overview about antibiotic resistance, and talked about his plan to target bacterial phosphoethanolamine transferases to restore colistin sensitivity in colistin-resistant bacteria. Vito summarised current strategies that have been investigated and employed to degrade PFAS, and outlined his plan to study the underlying … Read more

New paper in International Journal of Biological Macromolecules

Congratulations Dr Nabangshu Sharma for his new “first author” paper at the International Journal of Biological Macromolecules (Impact factor: 6.953). The paper describes Nabangshu’s work on the characterisation a novel laccase from Sulfitobacter indolifex, and its optimisation and application as a biocatalyst for the decolourisation of organic dyes. You can read the paper by following … Read more

Dr Nabangshu Sharma

Big congratulations to Nabangshu for successfully passing his PhD oral examination today. Nabangshu performed very well during the oral. He gave a very clear presentation about his findings, actively engaged in discussions with his examiner, and showed excellent knowledge about his work. Getting a PhD is a well deserved achievement for Nabangshu, who led multiple … Read more

School Seminar by Nabangshu

Nabangshu gave a very engaging seminar on the use of enzymes to degrade environmental pollutants at today’s Friday School of Chemical Sciences Research Seminar series. Well done Nabangshu!

New Paper in Oncology & Therapy

Check out our new paper on the validation of TDP1 as an inhibition target for the development of new cancer chemosensitizers in Oncology & Therapy today. Thanks especially to Dr Euphemia Leung (ACSRC), Jinal and Dr Jóhannes Reynisson (Keele University) for your hard work. Well done everyone!

New Paper in ChemBioChem

Congratulations Dr Naasson Mbenza for our new paper in ChemBioChem. In this paper, Naasson found out CO is an inhibitor of the human oxygen sensing enzyme PHD2 by using CORM-2 as a in situ CO donor. Thanks Naasson for your perseverance and hard work, and to our collaborators for your help and support! You can … Read more

Winter 2021 Graduation – Drs Mbenza and Patel

Congratulations Dr Naasson Mbenza and Dr Jinal Patel for officially graduating with your PhD today at the 2021 Winter Graduation Ceremony. Sorry I couldn’t join your ceremony due to the Victoria lockdown but I am very proud of your achievements. Well done!

Setting Up New Laboratory at Bio21

Very excited that the first major delivery for the new laboratory has arrived today (centrifuges, pipettes & thermomixer in case you are curious) just in time before the imminent lockdown in Victoria. Looking forward to more deliveries and to finally start doing some experiments here at the Bio21 Institute. Thanks Vito (new MSc student) for … Read more

Seminar at La Trobe University

Thank you Dr Yuning Hong for hosting me today at the La Trobe Institute for Molecular Science. It was great to be able to visit in person, and thanks for the opportunity for us to share our work, and I really enjoyed learning about the interesting science that the Institute is doing!

Virtual Seminar at ANU

Thanks Dr Lee Alissandratos for your invitation to host me today for an online seminar at the Research School of Chemistry at ANU. It was a great opportunity to share our work and to make new networks & catching up with old friends & colleagues!

Dr Ryan Dixon

Congratulations Dr Ryan Dixon for successfully passing his PhD oral examination today! Ryan accomplished an amazing multidisciplinary PhD (with A/Prof. Sperry, Prof. Curtis and Ivan) that involved organic chemistry, chemical biology and cell biology to identify compounds and cellular targets that relates to neuroplasticity. He is now postdoc with Maurice at the FMHS! Well done … Read more

New Paper in BMCL

Congratulations Dr Oi Wei Mak and Nabangshu Sharma for our new paper in Bioorganic & Medicinal Chemistry Letters! In this work, Oi Wei applied virtual screening to identify novel inhibitors that disrupt the binding interactions between Hsp90 C-terminal domain and its co-chaperones. This was confirmed experimentally by Oi Wei and Nabangshu. Thanks also to our … Read more

On the Cover of RSC Medicinal Chemistry

Congratulation to Brooke that her paper on the covalent inhibition of Mycobacterium tuberculosis isocitrate lyase is being featured in the latest edition of the RSC Medicinal Chemistry! Read our paper: RSC Med. Chem., 2021,12, 57-61

Lorne Proteins 2021

Well done Nabangshu, Eva, Vicky and Brooke for your virtual poster presentation at today’s Lorne Proteins 2021 conference. Due to COVID-19 we are unable to attend in person this year but hopefully we will back back next year in 2022!

The Leung Group is moving to the University of Melbourne

Ivan relocated to the School of Chemistry and the Bio21 Institute at the University of Melbourne today. At the moment, the core of the Leung Group (Nabangshu, Mike, Brooke, Vicky, Eva, Praveen and Ryan) is still based at the University of Auckland. Thank you for your understanding and I will make sure there will be … Read more